Pseudoxanthoma elasticum, ocular manifestations, complications and treatment
| Autor: | Ioannis Ladas, Ioannis Tservakis, Dimitris Papaconstaninou, Marina Kardara, Chryssanthi Koutsandrea, Ilias Georgalas |
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| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
Visual acuity business.industry Vision Disorders Visual Acuity Clinical course Macular translocation Pseudoxanthoma elasticum medicine.disease Dermatology eye diseases Ophthalmology Elastic fibres Angioid streaks Retinal Diseases Humans Medicine sense organs Pseudoxanthoma Elasticum medicine.symptom business Organ system Optometry |
| Zdroj: | Clinical and Experimental Optometry. 94:169-180 |
| ISSN: | 1444-0938 0816-4622 |
| DOI: | 10.1111/j.1444-0938.2010.00559.x |
| Popis: | Pseudoxanthoma elasticum (PXE), also known as Groenblad syndrome, is an inherited disorder characterised by mineralisation and fragmentation of elastic fibres in a number of organs including the skin, eyes and arterial blood vessels. The clinical manifestations of PXE centre on three major organ systems: skin, cardiovascular system and the eyes. This review focuses on the ocular manifestations of pseudoxanthoma elasticum, namely, peau d'orange, angioid streaks and choroidal neovascularisation, the clinical course of patients, the diagnostic approaches and current therapeutic strategies, such as laser photocoagulation whether transpupillary thermotherapy or photodynamic therapy, macular translocation surgery and anti-vascular endothelial growth factor treatment. |
| Databáze: | OpenAIRE |
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