Pterocarpenes elicited by Aspergillus caelatus in peanut (Arachis hypogaea) seeds
| Autor: | Shabana I. Khan, Scott A. Neff, Nurhayat Tabanca, Anthony J. De Lucca, David E. Wedge, Victor S. Sobolev, James B. Gloer |
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| Rok vydání: | 2010 |
| Předmět: |
Antifungal Agents
Gram-negative bacteria Arachis Pterocarpans Gram-positive bacteria Antineoplastic Agents Aspergillus flavus Microbial Sensitivity Tests Plant Science Horticulture Nitric Oxide Biochemistry Microbiology Fusarium Chlorocebus aethiops Colletotrichum Animals Humans Nuclear Magnetic Resonance Biomolecular Vero Cells Molecular Biology Antibacterial agent Aspergillus Molecular Structure biology Anti-Inflammatory Agents Non-Steroidal NF-kappa B food and beverages General Medicine Fungi imperfecti biology.organism_classification Anti-Bacterial Agents Arachis hypogaea Seeds Botrytis Reactive Oxygen Species Bacteria |
| Zdroj: | Phytochemistry. 71:2099-2107 |
| ISSN: | 0031-9422 |
| DOI: | 10.1016/j.phytochem.2010.09.018 |
| Popis: | The substituted pterocarpenes named aracarpene-1 (1) and aracarpene-2 (2) were isolated from wounded peanut seeds challenged by a strain of Aspergillus caelatus. The structures of these putative phytoalexins were determined by interpretation of NMR and MS data. The aracarpenes were investigated for their antifungal and antibacterial activities as well as antioxidant, anti-inflammatory, and cytotoxic activities in mammalian cells. Aracarpene-2 demonstrated high antibacterial properties against tested gram-positive and gram-negative bacteria, whereas aracarpene-1 displayed low antibacterial properties against the same bacteria. Both compounds had no antifungal activity against Aspergillus flavus. Together with peanut stilbenoids that are also produced in the challenged seeds, these compounds may represent a class of low-molecular weight peanut metabolites with a defensive role(s) against pathogenic microorganisms. |
| Databáze: | OpenAIRE |
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