Isolated Schwannoma of the Olfactory Groove: A Case Report
| Autor: | João Noberto Stavale, José Franscisco de Góis Filho, Isabela Naria Dias Sanchez, Bruna Barros Cavalcante, Flávio Aurélio Parente Settanni, Luiz Augusto Nascimento |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Pathology
medicine.medical_specialty neoplasms lcsh:Medicine Schwannoma Article Meningioma head and neck neoplasms Olfactory nerve Tecidos paranasal sinuses otorhinolaryngologic diseases Medicine Olfactory Groove Trigeminal nerve business.industry lcsh:R skull base Anatomy neurilemmoma nerve tissue medicine.disease lcsh:Otorhinolaryngology lcsh:RF1-547 Neoplasias Skull medicine.anatomical_structure Paranasal sinuses Otorhinolaryngology Anterior cranial fossa olfactory nerve Olfato business |
| Zdroj: | International Archives of Otorhinolaryngology, Vol 19, Iss 01, Pp 093-095 (2015) Repositório Institucional da UnB Universidade de Brasília (UnB) instacron:UNB International Archives of Otorhinolaryngology |
| ISSN: | 1809-4864 1809-9777 |
| DOI: | 10.1055/s-0033-1353368 |
| Popis: | Introduction Schwannoma of the olfactory groove is an extremely rare tumor that can share a differential diagnosis with meningioma or neuroblastoma. Objectives The authors present a case of giant schwannoma involving the anterior cranial fossa and ethmoid sinuses. Case Report The patient presented with a 30-month history of left nasal obstruction, anosmia, and sporadic ipsilateral bleeding. Computed tomography of the paranasal sinuses revealed expansive lesion on the left nasal cavity extending to nasopharynx up to ethmoid and sphenoid sinuses bilaterally with intraorbital and parasellar extension to the skull base. Magnetic resonance imaging scan confirmed the expansive tumor without dural penetration. Biopsy revealed no evidence of malignancy and probable neural cell. Bifrontal craniotomy was performed combined with lateral rhinotomy (Weber-Ferguson approach), and the lesion was totally removed. The tumor measured 8.0 × 4.3 × 3.7 cm and microscopically appeared as a schwannoma composed of interwoven bundles of elongated cells (Antoni A regions) mixed with less cellular regions (Antoni B). Immunohistochemical study stained intensively for vimentin and S-100. Conclusion Schwannomas of the olfactory groove are extremely rare, and the findings of origin of this tumor is still uncertain but recent studies point most probably to the meningeal branches of trigeminal nerve or anterior ethmoidal nerves. |
| Databáze: | OpenAIRE |
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