Detection of Cysticercus antigens and antibodies in cerbrospinal fluid of patients with chronic meningitis
| Autor: | Hariharkrishnaiear Dhanya, Priyadarshi Soumyaranjan Sahu, Subhash Chandra Parija |
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| Rok vydání: | 2007 |
| Předmět: |
Pathology
medicine.medical_specialty Neurocysticercosis Antibodies Helminth Helminthiasis Enzyme-Linked Immunosorbent Assay Cerebrospinal fluid Antigen Agglutination Tests parasitic diseases Taenia solium medicine Animals Humans Meningitis biology business.industry Cysticercosis General Medicine medicine.disease medicine.drug_formulation_ingredient Infectious Diseases Antigens Helminth Chronic Disease Immunology biology.protein Antibody business |
| Zdroj: | Revista do Instituto de Medicina Tropical de São Paulo. 49:331-334 |
| ISSN: | 0036-4665 |
| Popis: | Chronic meningitism is a less frequent manifestation of neurocysticercosis caused by Taenia solium cysticerci. In the present study we used Co-agglutination (Co-A), a simple and rapid slide agglutination test to detect specific Cysticercus antigen in the 67 cerebrospinal fluid (CSF) samples from patients with chronic meningitis of unknown etiology. The results were compared with that of ELISA for detection of antibodies. Among these samples four (5.97%) were positive for Cysticercus antigen by Co-A test and six (8.95%) were positive for antibodies by ELISA. Two samples were positive by both Co-A and ELISA, two were positive only by Co-A and four were positive only by ELISA. In the present study, although Cysticercus antigen and antibodies were present in CSF samples from eight (11.94%) patients, we cannot affirm that all the cases of chronic meningitis are due to cysticercosis, but for any case of chronic meningitis of unknown origin, it would be useful to consider the possibility of cysticercal meningitis. |
| Databáze: | OpenAIRE |
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