Alternaria chartarum sclerokeratouveitis: A new fungus cause
| Autor: | Virginia Vanzzini-Zago, Luz Elena Concha del Río, Carolina Ramirez-Dominguez, Lourdes Arellanes-García |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Visual acuity medicine.drug_class Antibiotics Case Report Hypopyon Cornea medicine Alternaria chartarum Voriconazole biology business.industry fungi fungus RE1-994 Alternaria biology.organism_classification medicine.disease sclerokeratouveitis Dermatology Sclera Ophthalmology medicine.anatomical_structure medicine.symptom business Scleritis medicine.drug |
| Zdroj: | Taiwan Journal of Ophthalmology Taiwan Journal of Ophthalmology, Vol 11, Iss 2, Pp 190-192 (2021) |
| ISSN: | 2211-5072 2211-5056 |
| Popis: | We report a case of Alternaria chartarum sclerokeratouveitis with an unfavorable response to treatment. To the best of our knowledge, there are no previous reports of this fungus invading the sclera. A 68-year-old diabetic farmer male patient presented with a 3-week history of pain and redness and a decrease in visual acuity occurring 5 days before admittance in the right eye. Examination revealed severe mixed hyperemia and a scleral calcified plaque with a surrounding area of ischemia and lysis. The cornea showed diffuse infiltrates, stromal edema, and hypopyon. Initial scrapings were negative, and empiric antibiotics were started. After a fungus was reported, topical and systemic antifungals were initiated, but there was no clinical response. The eye was enucleated. A slow-growing fungus A. chartarum, resistant to voriconazole, was isolated. Fungal etiology must be kept in mind when dealing with infectious scleritis. Despite treatment, the outcome of this case was unfavorable due to the slow-growing nature of the fungus and this strain's resistance to voriconazole. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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