Genetic Characterization of Hantaviruses Transmitted by the Korean Field Mouse (Apodemus peninsulae), Far East Russia
| Autor: | Ikuo Takashima, Tatyana Kushnaryova, Raisa Slonova, Tetsuya Mizutani, Bai Zhong Cui, Kenji Maeda, Hiroaki Kariwa, Kumari G. Lokugamage, Jiro Arikawa, Takeshi Kurata, Leonid I. Ivanov, Kumiko Yoshimatsu, Daisuke Hayasaka, Vladimir A. Demenev, Nandadeva Lokugamage, Vladimir I. Volkov, Koichi Araki, Galina Kompanets, Takuya Iwasaki |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2002 |
| Předmět: |
Microbiology (medical)
Orthohantavirus Epidemiology Hantavirus Infections Molecular Sequence Data lcsh:Medicine Biology Antibodies Viral Far East Russia Russia lcsh:Infectious and parasitic diseases Mice Apodemus peninsulae Phylogenetics Sequence Homology Nucleic Acid hemorrhagic fever with renal syndrome Animals Humans lcsh:RC109-216 Phylogeny Hantavirus Base Sequence Phylogenetic tree Reverse Transcriptase Polymerase Chain Reaction Research lcsh:R Genetic Variation virus diseases social sciences biology.organism_classification Virology humanities Infectious Diseases Close relationship GenBank Carrier State DNA Viral RNA Viral HFRS Far East Hantavirus Infection geographic locations |
| Zdroj: | Emerging Infectious Diseases, Vol 8, Iss 8, Pp 768-776 (2002) Emerging Infectious Diseases |
| ISSN: | 1080-6059 1080-6040 |
| Popis: | In an epizootiologic survey of 122 rodents captured in Vladivostok, Russia, antibodies positive for hantavirus were found in Apodemus peninsulae (4/70), A. agrarius (1/39), and Clethrionomys rufocanus (1/8). The hantavirus sequences identified in two seropositive A. peninsulae and two patients with hemorrhagic fever with renal syndrome (HFRS) from the Primorye region of Far East Russia were designated as Solovey and Primorye, respectively. The nucleotide sequences of the Solovey, Primorye, and Amur (obtained through GenBank) sequences were closely related (>92% identity). Solovey and Primorye sequences shared 84% nucleotide identity with the prototype Hantaan 76-118. Phylogenetic analysis also indicated a close relationship between Solovey, Primorye, Amur, and other viruses identified in Russia, China, and Korea. Our findings suggest that the Korean field mouse (A. peninsulae) is the reservoir for a hantavirus that causes HFRS over a vast area of east Asia, including Far East Russia. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|