Focal Hepatic Masses: Enhancement Patterns with SH U 508A and Pulse-Inversion US
| Autor: | Korosh Khalili, Stephanie R. Wilson, Marcus J. Dill-Macky, Peter N. Burns |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Adult
Male medicine.medical_specialty Carcinoma Hepatocellular Contrast Media Sensitivity and Specificity Diagnosis Differential Lesion Vascularity Polysaccharides Humans Medicine Radiology Nuclear Medicine and imaging Aged Ultrasonography business.industry Liver Neoplasms Focal nodular hyperplasia Echogenicity Middle Aged medicine.disease Pulse inversion Liver Focal Nodular Hyperplasia Hepatocellular carcinoma Female Radiology medicine.symptom Hemangioma business Arterial phase |
| Zdroj: | Radiology. 222:95-102 |
| ISSN: | 1527-1315 0033-8419 |
| DOI: | 10.1148/radiol.2221010092 |
| Popis: | To evaluate the role of SH U 508A-enhanced ultrasonography (US) in the differentiation of focal hepatic masses.Contrast material-enhanced pulse inversion US was performed on 58 unknown hepatic lesions: 23 hepatocellular carcinomas, 10 focal nodular hyperplasias, 16 hemangiomas, and nine metastases. Selected images were sequentially reviewed by readers blinded to the final diagnosis. On a baseline image, they determined lesion echogenicity, and on a vascular image, the presence or absence of distinct vascularity. On an arterial phase interval-delay flash image and a postvascular image, they assessed enhancement of the lesion and liver. Responses were compared with confirmed diagnoses.Focal nodular hyperplasia was characterized by detectable vascularity and positive enhancement on interval-delay and postvascular scans (sensitivity, 83% [eight of 10 lesions]; specificity, 98% [40 of 41 lesions]). Hepatocellular carcinoma also showed detectable vascularity and positive enhancement on interval-delay images but no postvascular enhancement (sensitivity, 68% [14 of 20 lesions]; specificity, 74% [23 of 31 lesions]). Vascular imaging with SH U 508A did not contribute to the diagnosis of metastasis or hemangioma. However, no or weak enhancement during the arterial phase flash without postvascular enhancement produced a sensitivity of 83% (seven of eight lesions) and sensitivity of 77% (33 of 43 lesions) for metastasis. Peripheral nodular enhancement on arterial phase flash images was highly specific (98% [37 of 38 lesions]) but not sensitive (44% [six of 13 lesions]) for hemangioma.SH U 508A-enhanced pulse-inversion interval-delay flash and postvascular phase imaging are helpful in differential diagnosis of focal hepatic lesions. |
| Databáze: | OpenAIRE |
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