A lysosomal targeted fluorescent probe based on coumarin for monitoring hydrazine in living cells with high performance

Autor:	Jianbo Qu, Jian-Yong Wang, Jin-Hua Jiang, Zhi-Hao Zhang
Rok vydání:	2022
Předmět:	Subcellular organelle Chemistry General Chemical Engineering General Engineering Coumarin Fluorescence Analytical Chemistry chemistry.chemical_compound Hydrazines Coumarins Biophysics Humans Hydrazine (antidepressant) Lysosomes Cytotoxicity Selectivity Fluorescent Dyes HeLa Cells
Zdroj:	Analytical Methods. 14:17-21
ISSN:	1759-9679 1759-9660
DOI:	10.1039/d1ay01821c
Popis:	A lysosomal targeted fluorescent probe based on coumarin for monitoring hydrazine (N2H4) in living cells was designed and synthesised. The novel fluorescent probe Cou-Lyso-N2H4, in response to N2H4, exhibited good selectivity, low cytotoxicity, and lysosomal localization, which could be suitable for studying the harmfulness of N2H4 in subcellular organelles during various physiological processes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd133ccbf2a2ab9578b78a807d399242 https://doi.org/10.1039/d1ay01821c Zobrazit plný text záznamu