Author Correction: Smac mimetics and oncolytic viruses synergize in driving anticancer T-cell responses through complementary mechanisms

Autor: Pankaj Tailor, Keith C.K. Lau, Franz J. Zemp, Dae-Sun Kim, Andrea Rakic, Robin M. Yates, Chris Gafuik, Victor Naumenko, Chunfen Zhang, Saif Sikdar, Dale R. Balce, Matthias Ernst, Craig N. Jenne, Douglas J. Mahoney, Ben W. Ewanchuk, Himika Dastidar, Jahanara Rajwani
Jazyk: angličtina
Rok vydání: 2018
Předmět:
0301 basic medicine
Computer science
Science
T cell
General Physics and Astronomy
Antineoplastic Agents
Computational biology
CD8-Positive T-Lymphocytes
General Biochemistry
Genetics and Molecular Biology
Vesicular stomatitis Indiana virus
Mitochondrial Proteins
03 medical and health sciences
Mice
Biomimetic Materials
Cell Line
Tumor
medicine
Animals
Humans
Author Correction
lcsh:Science
Oncolytic Virotherapy
Mice
Inbred BALB C
Multidisciplinary
030102 biochemistry & molecular biology
Intracellular Signaling Peptides and Proteins
General Chemistry
Neoplasms
Experimental
Smac mimetics
Combined Modality Therapy
Spelling
Oncolytic virus
Mice
Inbred C57BL
Oncolytic Viruses
Thiazoles
medicine.anatomical_structure
Treatment Outcome
ComputingMethodologies_DOCUMENTANDTEXTPROCESSING
Female
lcsh:Q
Apoptosis Regulatory Proteins
Zdroj: Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
Nature Communications
ISSN: 2041-1723
Popis: Second mitochondrial activator of caspase (Smac)-mimetic compounds and oncolytic viruses were developed to kill cancer cells directly. However, Smac-mimetic compound and oncolytic virus therapies also modulate host immune responses in ways we hypothesized would complement one another in promoting anticancer T-cell immunity. We show that Smac-mimetic compound and oncolytic virus therapies synergize in driving CD8
Databáze: OpenAIRE
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