Intraluminal micromanometry: an evaluation of the dynamic performance of micro-extrusions and sleeve sensors
| Autor: | Taher Omari, Malcolm Bakewell, Robert Fraser, Charles-Henri Malbert, Geoffrey Davidson, John Dent |
|---|---|
| Přispěvatelé: | ProdInra, Migration, Station de recherches porcines, Institut National de la Recherche Agronomique (INRA) |
| Předmět: |
medicine.medical_specialty
Materials science Physiology Manometry [SDV]Life Sciences [q-bio] Rise rate Pressure rise 03 medical and health sciences 0302 clinical medicine Digestive System Physiological Phenomena Animals Laboratory medicine Animals Humans ComputingMilieux_MISCELLANEOUS Miniaturization Endocrine and Autonomic Systems Gastroenterology Infant Newborn Equipment Design Surgery [SDV] Life Sciences [q-bio] Perfusion medicine.anatomical_structure 030220 oncology & carcinogenesis Sphincter 030211 gastroenterology & hepatology Infant Premature Biomedical engineering |
| Zdroj: | Flinders University PURE Journal of Neurogastroenterology and Motility Journal of Neurogastroenterology and Motility, Korean Society of Neurogastroenterology and Motility, 1996, 8, pp.241-245 |
| ISSN: | 2093-0879 2093-0887 |
| Popis: | Conventional manometric techniques are unsuitable for studies in premature infants and small laboratory animals. We have therefore developed silicone rubber 5-lumen and 10-lumen micromanometric extrusions with an o.d. 2.0 mm and lumina of 0.35 mm i.d. This study evaluates the suitability of microextrusions for intraluminal perfusion manometry. Pressure offset, post-occlusion pressure rise rate and sphincter model studies were used to assess the manometric performance of the extrusions and a miniature sleeve sensor (25 mm long) at infusion rates of 0.01-0.1 mL min-1. Micro-extrusions (5-lumen/10-lumen, respectively) had offsets (per 100 cm of length) of 3.8/5.0 mmHg at 0.01 mL min-1 and 25.6/26.2 mmHg at 0.1 mL min-1 and rise rates (in 160 cm lengths) of 64/43 mmHg sec-1 at 0.01 mL min-1 and 330/224 mmHg sec-1 at 0.1 mL min-1. Infusion rates 0.025 mL min-1 produced rise rates 100 mmHg sec-1. The miniature sleeve sensor had minimal resistance to perfusion, rise rates of 3 mmHg sec-1 at 0.01 mL min-1 and 23 mmHg sec-1 at 0.1 mL min-1 and recorded pressure as accurately as a side hole. We conclude that the performance of micromanometric extrusions and sleeves is sufficient for intraluminal perfusion manometry. |
| Databáze: | OpenAIRE |
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