Spectrum and frequency of ophthalmologic manifestations in patients with inflammatory bowel disease: A prospective single-center study
| Autor: | Margarita Kitsanou, Dimitrios K. Christodoulou, Vasileios Theopistos, Nikolaos Trakos, Epameinondas V. Tsianos, Konstantinos Katsanos, Ioannis Asproudis, Taxiarchis Felekis |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Visual acuity Eye Diseases Adolescent Eye Diseases/diagnosis/*etiology genetic structures Population Steroids/adverse effects Inflammatory bowel disease Young Adult Crohn Disease Prevalence medicine Humans Immunology and Allergy Optic neuritis Prospective Studies education Aged Aged 80 and over education.field_of_study Crohn's disease Retinal vasculitis business.industry Incidence Gastroenterology Episcleritis Middle Aged Prognosis medicine.disease Ulcerative colitis Dermatology eye diseases Colitis Ulcerative/*complications/diagnosis/drug therapy Surgery Case-Control Studies Colitis Ulcerative Steroids Female medicine.symptom Crohn Disease/*complications/diagnosis/drug therapy business |
| Zdroj: | Inflammatory Bowel Diseases. 15:29-34 |
| ISSN: | 1078-0998 |
| DOI: | 10.1002/ibd.20584 |
| Popis: | Background: The frequency and spectrum of ophthalmologic manifestations in patients with inflammatory bowel disease (IBD) has been reported to vary among studies; however, rare and silent manifestations have not been extensively studied. Methods: This was a prospective study of 60 patients diagnosed with IBD who underwent full ophthalmologic examination, including visual acuity, slit lamp examination of the anterior segments, intraocular pressure, and fundus examination accompanied by color photography. Thirty-seven (61,7%) patients were diagnosed with ulcerative colitis (UC) and 23 (38,3%) with Crohn's disease (CD). Data from 276 control individuals were used for the determination of the prevalence of dry eye in our area. Results: Ophthalmologic manifestations were diagnosed in 26 (43%) patients (14 UC, 12 CD; 12 males and 14 females). Conjunctivitis was diagnosed in 1 patient (CD), episcleritis in 2 patients (UC), and iridocyclitis in 3 (CD). Fundus examination showed 1 patient (CD) with unilateral choroiditis, 1 (UC) with retinal vasculitis, and 1 (CD) with optic neuritis. Retinal pigment epithelium disturbances (RPED) were present in 3 patients (1 CD, 2 UC) and 2 had serous retinal detachment. In total, 13/60 patients (22%) had dry eye compared with the 11% prevalence in controls. Eight patients developed glucocorticosteroid-induced cataracts, 2 of them treated surgically. Conclusions: This study demonstrated the prevalence of the spectrum of ophthalmologic manifestations in the IBD population, including some rare and silent findings that may merit consideration and early intervention. (Inflamm Bowel Dis 2008) |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text