Gas kinetics during nitrous oxide analgesia for labour
| Autor: | Anders Bengtsson, Ola Stenqvist, S. Einarsson, J. P. Bengtson, H. Norén |
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| Rok vydání: | 1996 |
| Předmět: |
inorganic chemicals
Adult Nitrous Oxide chemistry.chemical_element Oxygen Drug Administration Schedule chemistry.chemical_compound Pregnancy Hyperventilation medicine Humans Hypoxia Inhalation business.industry Nitrous oxide Hypoxia (medical) Analgesics Non-Narcotic Carbon Dioxide Kinetics Anesthesiology and Pain Medicine chemistry Anesthesia Carbon dioxide Analgesia Obstetrical Limiting oxygen concentration Female medicine.symptom business Respiratory minute volume |
| Zdroj: | Anaesthesia. 51(5) |
| ISSN: | 0003-2409 |
| Popis: | Summary Hypoxaemia may occur after hyperventilation with nitrous oxide during labour. The purpose of this study was to assess whether diffusion hypoxia is a contributory factor. Twenty-four parturients were randomly allocated to receive 50 or 70% nitrous oxide in oxygen. The median nitrous oxide inhalation time per contraction was 58 s and 33 s, respectively. The end-tidal carbon dioxide and the minute ventilation remained unchanged. The end-tidal oxygen concentration was lowest at 120s, reaching 15.4% in both groups. The oxygen saturation did not differ between the groups with a lowest median value of 96% before the start of nitrous oxide inhalation. Two parturients had episodes ofdesaturation. Both had low end-tidal oxygen concentrations in association with the desaturation but, as the end-tidal nitrous oxide concentrations were low, the desaturations could not be attributed to diffusion hypoxia. |
| Databáze: | OpenAIRE |
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