Possible role of the scintigraphic estimation of the relative liver perfusion in the diagnosis and therapy of liver carcinomas
| Autor: | Dragana Sobic-Saranovic, Irena B Radoman, Vladimir B. Obradovic, Mirjana Stojkovic, Snezana Lukic, Smiljana V. Pavlovic, Slavko Knezevic, Milica Lj. Stojković, Milorad Petrovic |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Liver perfusion
medicine.medical_specialty Carcinoma Hepatocellular medicine.medical_treatment Hemodynamics Scintigraphy 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Liver tissue Humans Medicine Radionuclide Angiography Sodium Pertechnetate Tc 99m Chemotherapy medicine.diagnostic_test Portal Vein business.industry Liver Neoplasms General Medicine medicine.disease 3. Good health 030220 oncology & carcinogenesis Hepatocellular carcinoma Radiology Radiopharmaceuticals Differential diagnosis business Perfusion Liver Circulation |
| Zdroj: | Acta chirurgica Iugoslavica. 58:33-38 |
| ISSN: | 2406-0887 0354-950X |
| DOI: | 10.2298/aci1101033s |
| Popis: | Background: The aim of the study is evaluation of the possible role of the scintigraphic estimation of the relative liver perfusion in diagnosis and the choice of treatment of liver carcinomas. Material and methods: Hepatic perfusion index was obtained by dynamic scintigraphy in 126 patients. Results: In the control group values did not differ from the value in the patients with benign tumors (p>0.05). However, in hepatocellular carcinoma and liver metastases of different tumors, HPI values were significantly decreased in comparison to controls and benign tumors (p0.05). The values were especially low in the patients with malignant diseases in the liver accosciated with vascular disturbances in the portal system. Conclusion: HRA could be easily done during the different conventional nuclear medicine methods. It can be an useful method for the assessment of different degrees of hemodynamic alterations in portal system, for differential diagnosis of benign and malignant liver tumors, as well as for assessment of the liver tissue and tumor perfusion, which might be helpful in the decision making for the undertaking of intraarterial (radionuclide, chemotherapy etc.) therapy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|