Comparative trial of iohexol 350, a non-ionic contrast medium, with diatrizoate (Urografin 370) in left ventriculography and coronary arteriography
| Autor: | I D Sullivan, R J Wainwright, E Sowton, J F Reidy |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Adult
Male medicine.medical_specialty Heart Ventricles Iohexol Contrast Media Blood Pressure Diatrizoate Chest pain Electrocardiography QRS complex Double-Blind Method Heart Rate Triiodobenzoic Acids Internal medicine medicine Humans ST segment Aged Clinical Trials as Topic medicine.diagnostic_test business.industry Angiocardiography Middle Aged Contrast medium Blood pressure Cardiology Iodobenzoates Female medicine.symptom Cardiology and Cardiovascular Medicine business Research Article medicine.drug |
| Zdroj: | Heart. 51:643-647 |
| ISSN: | 1355-6037 |
| DOI: | 10.1136/hrt.51.6.643 |
| Popis: | In a prospective double blind randomised study in 25 consecutive patients a conventional ionic contrast medium (Urografin 370) was compared with the new non-ionic medium iohexol 350 ( Omnipaque ) in left ventriculography and coronary arteriography. In left ventriculography there was a clear patient preference for iohexol by both a visual analogue scale and independent observer assessment. Iohexol also induced a smaller increase in heart rate or decrease in systolic blood pressure than Urografin. In coronary arteriography iohexol resulted in a smaller reduction in heart rate and systolic blood pressure, a smaller maximum increase in RR interval, less prolongation of the PQ and QT intervals and QRS duration, and a lower incidence of induced chest pain, ST segment depression, or T wave deflection. |
| Databáze: | OpenAIRE |
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