PERITONEAL WASH CYTOLOGY POSITIVITY IN CLINICALLY AND RADIOLOGICALLY PROVEN NON-METASTATIC ADENOCARCINOMA STOMACH – A TERTIARY CARE HOSPITAL STUDY

Autor: Sasi Malayan Parambil, Rajesh Mithalavalaram Raghavan, Abdulla Kunnummal Palathinkara
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Journal of Evidence Based Medicine and Healthcare, Vol 3, Iss 21, Pp 917-922 (2016)
ISSN: 2349-2570
2349-2562
Popis: BACKGROUND The presence of intra-peritoneal free cancer cells (IPFCC) in adenocarcinoma stomach has been proven to be associated with grim prognosis and is staged as M1 disease in latest TNM staging. Major resections are not indicated in these patients that will add to the morbidity and increase the cost and duration of hospital stay and also delay the commencement of palliative chemotherapy. MATERIALS AND METHODS Study was conducted in a tertiary care apex institute in Kerala, India. 60 consecutive cases of clinically and radiologically proven non-metastatic adeno carcinoma stomach with tissue diagnosis, who were being planned for curative resection, were selected and subjected to preoperative laparoscopic peritoneal washing. 300 ml of normal saline was introduced to peritoneal cavity. Which was aspirated after irrigating all surfaces of the peritoneal cavity. Sample was centrifuged, stained with Papanicolaou stain and cytological analysis for IPFCC was done from the Department of Pathology. Statistical analysis was done using SPSS software version 18.1 and p-value
Databáze: OpenAIRE