Depressed female cynomolgus monkeys (Macaca fascicularis) display a higher second-to-fourth (2D:4D) digit ratio
| Autor: | Qingyuan Wu, Xun Yang, Wei Li, Bin Lian, Yong He, Ling-Yun Luo, Peng Xie, Chao-Hua Qu, Jianguo Zhang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Digit ratio
Physiology Major depressive disorder Fingers 03 medical and health sciences 0302 clinical medicine lcsh:Zoology Animals Medicine lcsh:QL1-991 Risk factor Cynomolgus monkey Ecology Evolution Behavior and Systematics Testosterone Depression (differential diagnoses) 030304 developmental biology 0303 health sciences Core (anatomy) Behavior Animal Ecology Depression business.industry Numerical digit Finger length Macaca fascicularis medicine.anatomical_structure Female Animal Science and Zoology Forelimb business 030217 neurology & neurosurgery Reports |
| Zdroj: | Zoological Research, Vol 40, Iss 3, Pp 219-225 (2019) Zoological Research |
| ISSN: | 2095-8137 |
| Popis: | This research aimed to provide evidence of a relationship between digit ratio and depression status in the cynomolgus monkey (Macaca fascicularis). In stable cynomolgus monkey social groups, we selected 15 depressed monkeys based on depressive-like behavioral criteria and 16 normal control monkeys. All animals were video recorded for two weeks, with the duration and frequency of the core depressive behaviors and 58 other behaviors in 12 behavioral categories then evaluated via behavioral analysis. Finger lengths from the right and left forelimb hands of both groups were measured by X-ray imaging. Finger length and digit ratio comparisons between the two groups were conducted using Student’s t-test. In terms of the duration of each behavior, significant differences emerged in “Huddling” and five other behavioral categories, including Ingestive, Amicable, Parental, Locomotive, and Resting. In addition to the above five behavioral categories, we found that depressed monkeys spent less time in parental and rubbing back and forth behaviors than the control group. Furthermore, the 4th fingers were significantly longer in the left and right hands in the control group relative to the depressed monkeys. The second-to-fourth (2D:4D) digit ratio in the left and right forelimb hands was significantly lower in the control group than that in the depressed group. Our findings revealed significant differences in finger lengths and digit ratios between depressed monkeys and healthy controls, which concords with our view that relatively high fetal testosterone exposure may be a protective factor against developing depressive symptoms (or that low fetal testosterone exposure is a risk factor). |
| Databáze: | OpenAIRE |
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