SMALL CELL CARCINOMA OF THE KIDNEY A Case Report
| Autor: | Masahide Mine, Shin-Ichi Kojima, Hideaki Sekine |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Pathology
medicine.medical_specialty Urology medicine.medical_treatment Vinblastine Small-cell carcinoma Stain Cytokeratin Antineoplastic Combined Chemotherapy Protocols Humans Medicine Carcinoma Small Cell Kidney biology business.industry Chromogranin A Middle Aged medicine.disease Kidney Neoplasms Nephrectomy Methotrexate medicine.anatomical_structure Doxorubicin Synaptophysin biology.protein Female Lymph Cisplatin business |
| Zdroj: | The Japanese Journal of Urology. 89:614-617 |
| ISSN: | 1884-7110 0021-5287 |
| DOI: | 10.5980/jpnjurol1989.89.614 |
| Popis: | We report a case of small cell carcinoma of the kidney in a 61-year-old female. Chief complaints were left lumbago, gross hematuria and high fever. The computed tomography revealed a large invasive tumor in the left renal pelvis with renal pedicle lymph nodes swelling. Systemic chemotherapy with methotrexate, vinblastine, doxorubicin and cisplatin (M-VAC) showed a considerable effect and left nephrectomy was performed. But she died within 3 months postoperatively. Histologically, the tumor was composed of hyperchromatic small cells with increased N/C ratio. Immunohistochemical studies revealed positive staining for chromogranin A, synaptophysin, NSE, EMA, cytokeratin, and argyrophilic (Grimelius) silver impregnation stain. Electron microscopy revealed neurosecretory granules also. In conclusion, the present case was diagnosed as small cell carcinoma of the kidney with only 12 similar cases reported in the world literature. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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