Superoxide Scavenging Activity of Gold, Silver, and Platinum Nanoparticles Capped with Sugar-based Nonionic Surfactants
| Autor: | Tomokazu Yoshimura, Keisuke Matsuoka, Yuka Nakatani, Tsubasa Akasaki |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Silver
030309 nutrition & dietetics General Chemical Engineering Metal Nanoparticles chemistry.chemical_element Nanoparticle Platinum nanoparticles Silver nanoparticle Superoxide dismutase Surface-Active Agents 03 medical and health sciences chemistry.chemical_compound 0404 agricultural biotechnology Glucosides Polymethacrylic Acids Pulmonary surfactant Superoxides Animals Particle Size Platinum 0303 health sciences biology Superoxide Dismutase Chemistry Superoxide Free Radical Scavengers 04 agricultural and veterinary sciences General Medicine General Chemistry 040401 food science Colloidal gold biology.protein Cattle Gold Nuclear chemistry |
| Zdroj: | Journal of Oleo Science. 68:847-854 |
| ISSN: | 1347-3352 1345-8957 |
| DOI: | 10.5650/jos.ess19079 |
| Popis: | Metal nanoparticles have the ability to remove superoxide via changes in the surface electronic states at the large surface area. Gold, silver, and platinum nanoparticles were prepared in the presence of three sugar-based nonionic surfactants using NaBH4 as a reducing agent. The surfactants (glycosyloxyethyl methacrylate: xGEMA) contain sugar oligomers of various lengths (x), are biodegradable, and act as protecting groups for the nanoparticles. Three types of xGEMA were used: dodecyl and hexadecyl chains containing amphiphilic oligomers (C12-3.0GEMA and C16-3.2GEMA) and multi-dodecyl chain with multiple sugar side chains (1.8C12-4.7GEMA). We found that the type of nonionic surfactant affected the size of the nanoparticles. The average size of the gold, silver, and platinum nanoparticles ranged from 1.9 to 6.6 nm depending on the surfactant. The trend in the size of gold nanoparticles in relation to the chosen surfactants was different from that for the silver and platinum nanoparticles. Moreover, the gold nanoparticles did not show effective antioxidant activity for superoxide, whereas the silver and platinum nanoparticles removed superoxide to a certain extent. The general order for superoxide scavenging activity increased in the following order: gold < platinum < silver. In particular, the largest size of silver nanoparticles capped with C16-3.2GEMA had a similar ability for the removal of superoxide as superoxide dismutase (ca. 3999 unit/mg) on the basis of the mass concentration. |
| Databáze: | OpenAIRE |
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