Quinoa starch microspheres for drug delivery: preparation and their characteristics

Autor: Yang LUO, Futai NI, Mingzhu GUO, Juan LIU, Huan CHEN, Sitong ZHANG, Yanli LI, Guang CHEN, Gang WANG
Rok vydání: 2022
Předmět:
Zdroj: Food Science and Technology v.42 2022
Food Science and Technology (Campinas)
Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA)
instacron:SBCTA
Food Science and Technology, Volume: 42, Article number: e126421, Published: 18 MAR 2022
ISSN: 1678-457X
0101-2061
DOI: 10.1590/fst.126421
Popis: Quinoa starch microparticles (QSMs) fabricated with unhydrolyzed quinoa starch (QS) by inverse microemulsion technology could be used as medicine delivery and cosmetic accessories. The size distribution of QSMs was uniform at 28.5 μM, and the adsorption capacity of methylene blue was 0.82 mg/ g. The optimum preparation process was as follows: a QS mass fraction of 9%, an epoxy chloropropane content of 1%, an amount of oil phase of 100 mL, a span 80 of 3 mg/mL, and a stirring speed of 400 r/min for 3 h at room temperature and pressure. The QSMs were spherical, ellipsoidal in shape with the specific surface area of 1.676 m2/g. The crystallinity of the QSMs increased from 1.24% to 16.8% after crosslinking. The maximum thermal degradation temperature of the QSMs rose slightly than QS. It will be a promising material for application as a drug carrier and in cosmetics.
Databáze: OpenAIRE