Lipometabolism and Glycometabolism in Liver Diseases
| Autor: | Jinglin Wang, Xiaolei Shi, Haozhen Ren, Hao-ran Ding |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
lcsh:Medicine Physiology Review Article Carbohydrate metabolism General Biochemistry Genetics and Molecular Biology 03 medical and health sciences Liver disease Insulin resistance Medicine Animals Humans Pathological Metabolic function General Immunology and Microbiology business.industry Liver Diseases lcsh:R Lipid metabolism General Medicine medicine.disease Lipid Metabolism 030104 developmental biology Liver metabolism Liver Carbohydrate Metabolism business Homeostasis |
| Zdroj: | BioMed Research International BioMed Research International, Vol 2018 (2018) |
| ISSN: | 2314-6141 |
| Popis: | The liver is the main metabolic organ in the body especially in lipometabolism and glycometabolism. Carbohydrates and fats disorders can result in insulin resistance in the liver. Metabolic imbalance can even lead to life-threatening conditions. Therefore, it is essential to maintain the normal metabolic function of the liver. When the liver is in a pathological state, liver metabolism homeostasis is damaged, and metabolic disorders will further aggravate liver disease. Consequently, it is essential to determine the relationship between liver diseases and metabolic disorders. Here we review a lot of evidence that liver diseases are closely related to lipometabolism and glycometabolism. Although the disorder of the liver metabolism is caused by different liver diseases, the break of metabolic balance is determined by changes in the state of the liver. We discuss the relationship between liver disease and metabolic changes, outline the process of how metabolic changes are regulated by liver diseases, and describe the role which metabolic changes play in the process and prognosis of liver disease. |
| Databáze: | OpenAIRE |
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