Targeting acetate metabolism: Achilles’ nightmare
| Autor: | Katelyn D. Miller, Zachary T. Schug |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Cancer Research
Tumour heterogeneity Acetate-CoA Ligase Antineoplastic Agents Acetates 03 medical and health sciences Mice 0302 clinical medicine Neoplasms medicine Animals Humans Molecular Targeted Therapy Enzyme Inhibitors business.industry Comment Acetate metabolism Nightmare Metabolic pathway Treatment Outcome Oncology 030220 oncology & carcinogenesis Cancer cell Cancer research medicine.symptom Altered metabolism business Metabolic Networks and Pathways |
| Zdroj: | Br J Cancer |
| Popis: | Recent advances in our understanding of tumour heterogeneity alongside studies investigating altered metabolism within transformed tissue have identified metabolic pathways critical to cancer cell survival. Leveraging this information presents a promising new avenue for the generation of cancer-specific therapeutics and improved patient outcomes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|