Thoraco-abdominal high-pitch dual-source CT angiography: experimental evaluation of injection protocols with an anatomical human vascular phantom
| Autor: | Thomas Frauenfelder, Gilbert Puippe, André Plass, Anna Winklehner, Peter Hasenclever, Stephan Baumueller |
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| Přispěvatelé: | University of Zurich, Puippe, G D |
| Rok vydání: | 2011 |
| Předmět: |
Radiography
Abdominal medicine.medical_specialty Cardiac output Iohexol Dual source ct Contrast Media 610 Medicine & health Sensitivity and Specificity Imaging phantom Radiography Dual-Energy Scanned Projection Text mining medicine.artery medicine High pitch 2741 Radiology Nuclear Medicine and Imaging Humans Radiology Nuclear Medicine and imaging Computed tomography angiography Aorta medicine.diagnostic_test Dose-Response Relationship Drug business.industry 10042 Clinic for Diagnostic and Interventional Radiology Phantoms Imaging Angiography Reproducibility of Results General Medicine 10020 Clinic for Cardiac Surgery Radiographic Image Enhancement Radiography Thoracic Radiology Nuclear medicine business Tomography X-Ray Computed |
| Zdroj: | European journal of radiology. 81(10) |
| ISSN: | 1872-7727 |
| Popis: | To experimentally evaluate three different contrast injection protocols at thoraco-abdominal high-pitch dual-source computed tomography angiography (CTA), with regard to level and homogeneity of vascular enhancement at different cardiac outputs.A uniphasic, a biphasic as well as an individually tailored contrast protocol were tested using a human vascular phantom. Each protocol was scanned at 5 different cardiac outputs (3-5L/min, steps of 0.5L/min) using an extracorporeal cardiac pump. Vascular enhancement of the thoraco-abdominal aorta was measured every 5 cm. Overall mean enhancement of each protocol and mean enhancement for each cardiac output within each protocol were calculated. Enhancement homogeneity along the z-axis was evaluated for each cardiac output and protocol.Overall mean enhancement was significantly higher in the uniphasic than in the other two protocols (all p.05), whereas the difference between the biphasic and tailored protocol was not significant (p=.76). Mean enhancement among each of the 5 cardiac outputs within each protocol was significantly different (all p.05). Only within the tailored protocol mean enhancement differed not significantly at cardiac outputs of 3.5L/min vs. 5L/min (484 ± 25 HU vs. 476 ± 19 HU, p=.14) and 4 vs. 5L/min (443 ± 49 HU vs. 476 ± 19 HU, p=.05). Both, uniphasic and tailored protocol yielded homogenous enhancement at all cardiac outputs, whereas the biphasic protocol failed to achieve homogenous enhancement.This phantom study suggests that diagnostic and homogenous enhancement at thoraco-abdominal high-pitch dual-source CTA is feasible with either a uniphasic or an individually tailored contrast protocol. |
| Databáze: | OpenAIRE |
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