The Participation of Microglia in Neurogenesis: A Review
| Autor: | Idoia Blanco-Luquin, Maite Mendioroz, Diego R. Pérez-Rodríguez |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0303 health sciences
Brain organization Microglia General Neuroscience Neurogenesis microglia Neurosciences. Biological psychiatry. Neuropsychiatry Review Biology adult neurogenesis 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure nervous system age inflammation medicine neurodegenerative diseases Neuroscience 030217 neurology & neurosurgery Brain function 030304 developmental biology RC321-571 |
| Zdroj: | Brain Sciences Brain Sciences, Vol 11, Iss 658, p 658 (2021) |
| ISSN: | 2076-3425 |
| Popis: | Adult neurogenesis was one of the most important discoveries of the last century, helping us to better understand brain function. Researchers recently discovered that microglia play an important role in this process. However, various questions remain concerning where, at what stage, and what types of microglia participate. In this review, we demonstrate that certain pools of microglia are determinant cells in different phases of the generation of new neurons. This sheds light on how cells cooperate in order to fine tune brain organization. It also provides us with a better understanding of distinct neuronal pathologies. |
| Databáze: | OpenAIRE |
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