In vitro biological response of cancer and normal tissue cells to proton irradiation not affected by an added magnetic field

Autor:	Antje Knopf, Marc-Jan van Goethem, Harry Kiewit, Johannes A. Langendijk, Sytze Brandenburg, Robert P. Coppes, Marco Kempers, Peter W. Nagle, Peter van Luijk
Přispěvatelé:	Research unit Medical Physics, Damage and Repair in Cancer Development and Cancer Treatment (DARE), Guided Treatment in Optimal Selected Cancer Patients (GUTS)
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	Proton Magnetic Field Therapy Quantitative Biology::Tissues and Organs medicine.medical_treatment Physics::Medical Physics Normal tissue Adenocarcinoma of Lung THERAPY Salivary Glands Quantitative Biology::Cell Behavior 030218 nuclear medicine & medical imaging PHYSICS Mice 03 medical and health sciences 0302 clinical medicine Proton Therapy medicine Organoid Animals Humans Radiology Nuclear Medicine and imaging Irradiation Proton therapy Tumor Stem Cells Cancer Hematology medicine.disease equipment and supplies Magnetic Resonance Imaging In vitro Magnetic field Mice Inbred C57BL Radiation therapy Organoids HEK293 Cells Oncology A549 Cells 030220 oncology & carcinogenesis Biophysics Physics::Accelerator Physics Female Protons human activities MRI RADIOTHERAPY
Zdroj:	Radiotherapy and Oncology, 137, 125-129. ELSEVIER IRELAND LTD
ISSN:	1879-0887 0167-8140
Popis:	To optimize beam delivery and conformality of proton therapy, MRI integration has been proposed. Therefore, we investigated if proton irradiation in a magnetic field would change biological responses. Our data in cancer cell lines and stem cell-derived organoid models suggest that a magnetic field does not modify the biological response. (C) 2019 Elsevier B.V. All rights reserved.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dce54fbf73a29c8b0f7893fa0395ef65 https://research.rug.nl/en/publications/3a82ad77-cdf8-4cbe-b2b1-855d355d0cdb Zobrazit plný text záznamu Full Text from ScienceDirect