Azide-induced mutagenesis in gram-negative bacteria is recA-and lexA-independent
| Autor: | Maria Szwacka, Zygmunt Cieśla, T. Kłopotowski |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
DNA Replication
Salmonella typhimurium Azides Gram-negative bacteria DNA Repair Genotype Health Toxicology and Mutagenesis Mutant medicine.disease_cause Microbiology chemistry.chemical_compound Genetics medicine Escherichia coli Molecular Biology RecBCD Recombination Genetic biology Mutagenesis biology.organism_classification Molecular biology chemistry bacteria Azide Repressor lexA DNA Mutagens |
| Zdroj: | Mutation research. 62(2) |
| ISSN: | 0027-5107 |
| Popis: | Azide-induced mutagenesis was investigated in Salmonella typhimurium and Escherichia coli . Azide was highly effective in inducing mutations in uvrB, uvrB recA and uvrB recB mutants of S. typhimurium . The mutagenic effect of azide was also observed in uvrA lexA mutants of E. coli K12 and E. coli B/r. These results suggest that azide-induced mutagenesis is due to mis-replication of DNA. |
| Databáze: | OpenAIRE |
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