Development of a flexible inflow cannula with titanium inflow tip for the NEDO biventricular assist device
| Autor: | Daniel Oestmann, Shinichi Tsujimura, Seiji Ichikawa, Toshiyuki Shinohara, Yukihiko Nosé, Kuniyoshi Watanabe, Atsushi Hata, Seiichi Ito, Toshimasa Asai, Tadashi Motomura |
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| Rok vydání: | 2004 |
| Předmět: |
animal structures
Materials science Biventricular assist device Biomedical Engineering Biophysics chemistry.chemical_element Bioengineering Inflow Beak shape Catheterization Biomaterials Animals Titanium Coronary Stenosis General Medicine Anatomy Equipment Design equipment and supplies Cannula chemistry Ventricle cavity Production model Cattle Inflow cannula Heart-Assist Devices Plastics Biomedical engineering |
| Zdroj: | ASAIO journal (American Society for Artificial Internal Organs : 1992). 50(4) |
| ISSN: | 1058-2916 |
| Popis: | A newly designed flexible inflow cannula has been developed for a biventricular assist device (BVAD). The inflow tip was designed for long-term ventricle drainage. Considering the anatomic differences between the right and left ventricles, a flexible inflow cannula, as a mass production model with a titanium tip, was developed and investigated in chronic BVAD animal experiments using the NEDO permanently implantable centrifugal blood pump. These flexible inflow cannulae consist of flexible plastic tubing with wire supported, titanium left and right tips. The right titanium inflow tip was designed with inner and outer stoppers to be inserted into the right ventricle wall and a beak shape to avoid sucking. The left tip was designed to be inserted into the left ventricle cavity. Five chronic BVAD bovine studies were performed to investigate the new beak shaped titanium tip. In these studies, the new beak shaped titanium tip and cannula prevented stenosis by a proliferation of pseudoneointimal, and supplied adequate blood flow to the pump without sucking. This newly designed inflow cannula with the beak shaped titanium tip was successfully implanted for 90 days. |
| Databáze: | OpenAIRE |
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