Comparison Between Graders in Detection of Diabetic Neovascularization With Swept Source Optical Coherence Tomography Angiography and Fluorescein Angiography
| Autor: | John W. Hinkle, Jonathan F. Russell, William E. Smiddy, Rehan M. Hussain, Giovanni Gregori, Thomas A. Lazzarini, Benjamin J. Fowler, Nicolas A. Yannuzzi, Stephen R. Russell, Liang Wang, Nathan L. Scott, Anita Barikian, Hasenin Al-khersan, Yingying Shi, Philip J. Rosenfeld, William J. Feuer, Nimesh A. Patel, Jayanth Sridhar, Seenu M. Hariprasad, Luis J. Haddock |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty education Visual Acuity Physical examination Retinal Neovascularization Article Neovascularization 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests Ophthalmology Humans Medicine False Positive Reactions In patient Fluorescein Angiography Grading (tumors) Retrospective Studies 030304 developmental biology 0303 health sciences Diabetic Retinopathy Ophthalmologists medicine.diagnostic_test business.industry Reproducibility of Results Retinal Vessels Retrospective cohort study Diabetic retinopathy Optical coherence tomography angiography Middle Aged medicine.disease Fluorescein angiography eye diseases 030221 ophthalmology & optometry Female medicine.symptom business Tomography Optical Coherence |
| Zdroj: | Am J Ophthalmol |
| ISSN: | 0002-9394 |
| Popis: | Purpose We compared the ability of ophthalmologists to identify neovascularization (NV) in patients with proliferative diabetic retinopathy using swept-source optical coherence tomography angiography (SS-OCTA) and fluorescein angiography (FA). Design Retrospective study comparing diagnostic instruments. Methods Eyes with proliferative diabetic retinopathy or severe nonproliferative diabetic retinopathy and a high suspicion of NV based on clinical examination were imaged using SS-OCTA and FA at the same visit. Two separate grading sets consisting of scrambled, anonymized SS-OCTA and FA images were created. The ground truth for presence of NV was established by consensus of 2 graders with OCTA experience who did not participate in the subsequent assessment of NV in this study. The 2 anonymized image sets were graded for presence or absence of NV by 12 other graders that included 2 residents, 6 vitreoretinal fellows, and 4 vitreoretinal attending physicians. The percentage of correct grading of NV using SS-OCTA and FA was assessed for each grader and across grader training levels. Results Forty-seven eyes from 24 patients were included in this study. Overall, the mean percentage of correct NV grading was 87.8% using SS-OCTA with B-scans and 86.2% using FA (P = .92). Assessing each grader individually, there was no statistically significant asymmetry in correct grading using SS-OCTA and FA. Conclusions Ophthalmologists across training levels were able to identify diabetic NV with equal accuracy using SS-OCTA and FA. Based on these results, SS-OCTA may be an appropriate standalone modality for diagnosing diabetic NV. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect