Diabetes Mellitus and Neuropathy Following Vacor Ingestion in Man
| Autor: | Rhoda Peal, Joseph M. Rubino, Donald Bishop, Allan Pont |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Adult
Male Niacinamide medicine.medical_specialty Suicide Attempted Autonomic Nervous System Diabetic Ketoacidosis Diabetes mellitus Internal medicine Internal Medicine medicine Humans Ingestion Rodenticide business.industry Phenylurea Compounds Nicotinic Acids Rodenticides Middle Aged medicine.disease Surgery Toxicity Nervous System Diseases Autonomic neuropathy business |
| Zdroj: | Archives of Internal Medicine. 139:185 |
| ISSN: | 0003-9926 |
| DOI: | 10.1001/archinte.1979.03630390039016 |
| Popis: | Two patients ingested Vacor, a rodenticide containing the active ingredient N -3 pyridylmethyl- N ′-p-nitrophenyl urea. Both patients developed ketosis-prone diabetes mellitus and severe autonomic neuropathy. Niacinamide therapy given nine hours after Vacor ingestion in one patient and 14 hours after ingestion in the other was not successful in preventing these sequelae. Physicians need to be aware of the toxicity of Vacor, and the potential therapeutic benefit of early niacinamide therapy. ( Arch Intern Med 139:185-187, 1979) |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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