Overview of virus and cancer relationships. Position paper
| Autor: | O Fernández-Capetillo, D Gracia, Joaquín Arribas, M Martín Jiménez, Rafael Bañares, M B Barragán, J.M. Eiros Bouza, J Tovar, Emilio Bouza, Luis Paz-Ares, A Torné, E Valencia, L Alemany, P Muñoz, Esteban Palomo, E Felip, J Bautista Mollar, Rogelio López-Vélez |
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| Rok vydání: | 2021 |
| Předmět: |
Microbiology (medical)
HPV Oncolytic virus viruses Review Cancer mortality Hepatitis C. HBV Virus Tumours EBV Neoplasms Tumor Virus Humans Medicine Papillomaviridae HHV-8 Tropism Cancer Pharmacology Vaccines business.industry Human Papillomavirus HIV virus diseases Oncogenes General Medicine Hepatitis B medicine.disease Virology Cancer-prevention Human T Lymphotropic Virus I Virus Diseases HTLV-1 Human Herpes Virus 8 HCV Etiology Position paper Oncogenic Viruses Cancer-economy business Epstein-Barr Virus Human Immunodeficiency Virus Biomedical sciences |
| Zdroj: | Revista Española de Quimioterapia |
| ISSN: | 1988-9518 0214-3429 |
| DOI: | 10.37201/req/058.2021 |
| Popis: | The role of certain viruses in the etiology of some tumors is today indisputable, but there is a lack, however, of annoverview of the relationship between viruses and cancer with amultidisciplinary approach. For this reason, the Health Sciences Foundation has convened a group of professionals from different areas of knowledge to discuss the relationship between viruses and cancer, and the present document is the result of these deliberations. Although viruses cause only 10-15% of cancers, advances in oncology research are largely due to the work done during the last century on tumor viruses. The clearest cancer-inducing viruses are: HPV, HBV, HCV, EBV and, depending on the geographical area, HHV-8, HTLV-1 and HIV. HPVs, for example, are considered to be the causative agents of cervical carcinomas and, more recently, of a proportion of other cancers. Among the Herpes viruses, the association with the development of neoplasms is well established for EBV and HHV-8. Viruses can also be therapeutic agents in certain neoplasms and, thus, some oncolytic viruses with selective tropism for tumor cells have been approved for clinical use in humans. It is estimated that the prophylaxis or treatment of viral infections could prevent at least 1.5 million cancer deaths per year. |
| Databáze: | OpenAIRE |
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