Effects of periosteal activation agent on bone repair and ingrowth

Autor: L. Russell Alberts
Rok vydání: 1987
Předmět:
Zdroj: Journal of Biomedical Materials Research. 21:429-442
ISSN: 1097-4636
0021-9304
Popis: A substance that activates the resting periosteum (PAA) was applied to the periosteal surface in two different healing models using the femurs of 2-kg male rabbits. The activation agent was applied to the periosteal surface over the sites of circular defects drilled through the lateral cortex in one model and over the sites of porous polyethylene implants placed in the lateral cortex and the medullary canal in the other model. Results failed to show that the agent either enhanced bone ingrowth into the porous implants or accelerated bony filling of the circular defects. However, there was indication of enhanced mineralization and periosteal callus formation as early as 24 h after application.
Databáze: OpenAIRE