Vitrectomy, Fluid—Gas Exchange and Transforming Growth Factor—Beta-2 for the Treatment of Traumatic Macular Holes
Autor: | Bert M. Glaser, Jeffrey S. Rubin, Stephen S. Pappas, Raymond N. Sjaarda, Robert P. Murphy, John T. Thompson |
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Rok vydání: | 1995 |
Předmět: |
Adult
Male Reoperation medicine.medical_specialty Visual acuity Adolescent genetic structures medicine.medical_treatment Eye disease Visual Acuity Vitrectomy Wounds Nonpenetrating Retina Eye Injuries Transforming Growth Factor beta Ophthalmology medicine Humans Fluorescein Angiography Child Vitreous surgery Macular hole Fluorocarbons business.industry Air Retinal Perforations medicine.disease Recombinant Proteins eye diseases Surgery Treatment Outcome Maculopathy Female sense organs Ophthalmic Solutions medicine.symptom Complication business Follow-Up Studies Retinopathy |
Zdroj: | Ophthalmology. 102:1840-1845 |
ISSN: | 0161-6420 |
Popis: | Purpose: To evaluate whether vitreous surgery is successful in closing full-thickness traumatic macular holes and whether there is subsequent improvement in visual acuity. Methods: Twelve eyes from 12 consecutive patients with traumatic macular holes underwent vitrectomy, fluid-gas exchange and instillation of bovine or recombinant transforming growth factor (TGF)-beta-2. Three of four eyes underwent repeat vitrectomy with TGF-beta-2 after the initial procedure failed to close the macular hole. Results: Eleven (92%) of 12 eyes had closure of the macular hole. Follow-up ranged from 3 to 33 months. Visual acuity improved by 2 or more lines in 8 (67%) of 12 eyes. Six (50%) of 12 eyes improved to 20/40 or better. All 3 eyes that underwent reoperation had successful closure of the macular hole and achieved 2 or more lines of visual improvement. Conclusion: Treatment of full-thickness traumatic macular holes with vitrectomy, fluid-gas exchange, and TGF-beta-2 may result in successful anatomic closure and visual improvement. |
Databáze: | OpenAIRE |
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