MAOA-uVNTR genotype predicts interindividual differences in experimental aggressiveness as a function of the degree of provocation

Autor: Catrin Wielpuetz, Yvonne Kuepper, Juergen Hennig, Phillip Grant
Rok vydání: 2013
Předmět:
Zdroj: Behavioural Brain Research. 247:73-78
ISSN: 0166-4328
DOI: 10.1016/j.bbr.2013.03.002
Popis: The MAOA-uVNTR has been suggested to play a role regarding aggression, however, results are inconsistent. We aimed at further elucidating potential effects of the MAOA-uVNTR on aggressiveness with respect to potential modulators: sex, experimental vs. trait aggressiveness and type of aggressiveness (proactive vs. reactive aggressiveness). We tested 239 healthy young adults (88 men/151 women). Participants were genotyped for the MAOA-uVNTR and performed a modified version of a competitive reaction time task - a commonly used and well established tool to elicit and measure aggressiveness. Furthermore, they completed a self-report scale measuring trait aggressiveness. We found a main effect of MAOA-uVNTR on a measure of reactive aggressiveness for both men and women, whereby the low-activity alleles of the MAOA-uVNTR were associated with substantially increased aggressive reactions (p
Databáze: OpenAIRE