| Autor: |
Larry Schut, Sue Barden Johnson, Julie Nygren, Lori Holden, Gabe J. Maletta, David Knopman, Maurice W. Dysken, J. Riley McCarten, Michael A. Kuskowski, Govind T. Vatassery, Stacy S. Skare, Mary Jelinski |
| Rok vydání: |
1993 |
| Předmět: |
|
| Zdroj: |
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 2(2) |
| ISSN: |
1545-7214 |
| Popis: |
To investigate the relationship between clinical response and haloperidol blood concentrations in Alzheimer's dementia (AD) patients with behavior problems, 29 AD inpatients were assigned to a fixed oral dosage of haloperidol (0.5 mg, 1.0 mg, or 2.0 mg) every 12 hours for 3 weeks. BEHAVE-AD ratings and concentrations of plasma and RBC haloperidol and reduced haloperidol were obtained on Days 8, 15, and 22. Although no significant linear or curvilinear relationships were apparent between percent of change on BEHAVE-AD and plasma or RBC haloperidol concentrations, a good response (change ≥ 30%) was observed in 55% of the patients who entered the study. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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