| Popis: |
Background and Objectives:Candidaspecies is one of the commensal microorganisms and a member of the oral cavity normal flora. In addition,Candida albicansis a microbiologic member of the oral cavity in children with dental caries. Currently, use of probiotics as a new biologic technique has attracted attention in order to prevent and control diseases.Enterococcus durans hasshown useful antioxidative properties and antibacterial and probiotic characteristics. The aim of this study was to evaluate the effect of probioticEnterococcus duranson adhesion ofCandida albicansinin vitro. Materials and Methods: In thisin vitrostudy, the standard strain bacteria of probioticE. durans (ATCC 6056) andCandida albicans (PTCC5027)and 10 clinical samples ofCandida albicansis provided. The adhesive inhibition ofCandida albicansvia microtiter plate was tested. Data were analyzed with repeated measure model. Statistical significance was set at P Results:This study showed that, Mean OD620 nm were in range of 0.45 to 0.49 and for OD490 nm were 0.33. Therefore, in presence of the probiotic strain, the biofilm ofCandida albicansadhesion were reduced. Conclusion: The first step in infection process is attachment and the adhesion ofCandida albicanscan be prohibited by use of probiotic such asE. durans. |
