Placental Transmogrification of the Lung, A Histologic Variant of Giant Bullous Emphysema
| Autor: | B. Sebek, M. Koomen, F. B. Askin, M. E. Fidler, M. A. Greco, C. C. Rizk |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Mediastinal Shift Pathology and Forensic Medicine Lesion medicine Humans Cyst Lung Respiratory distress business.industry Respiratory disease Anatomy medicine.disease Immunohistochemistry Radiography medicine.anatomical_structure Pulmonary Emphysema Female Surgery medicine.symptom Complication business Bulla (amulet) |
| Zdroj: | The American Journal of Surgical Pathology. 19:563-570 |
| ISSN: | 0147-5185 |
| DOI: | 10.1097/00000478-199505000-00008 |
| Popis: | Placental transmogrification of the lung was described by Chesney in 1978 as an unusual cystic lesion involving a single pulmonary lobe (3). We studied three additional cases with identical clinical and pathologic features. The patients were a 33-year-old woman and men aged 24 and 27 years. Each patient was first seen with respiratory distress; one had repeated pneumothoraces. Radiographically, an enlarging cystic lesion was present in a lower (two) or middle (one) lobe. The lesion had been present for 10 years in one patient. In two patients, mediastinal shift was noted. Lobectomy was curative in all instances. Grossly there was a uni- or paucilocular cyst lined by papillary structures. Microscopically, the papillae contained proliferating blood vessels, lymphoid nodules, smooth muscle, and fat. Sclerotic foci obliterated the vessels in some areas. The growth pattern and topography resembled those of placental villi. Systematic review of the histologic features in other lungs with marked emphysema revealed a spectrum of similar changes and suggested that the lesion in our patients may be a complication of bulla formation and is most likely the clinico-pathologic analog of the "vanishing lung" syndrome (idiopathic giant bullous emphysema). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|