Effect of paracentesis on metabolic activity in patients with advanced cirrhosis and ascites
| Autor: | Flemming Tofteng, Ulrik Becker, Inge Nordgaard-Lassen, Erik Frandsen, Anne Wilkens Knudsen, Aleksander Krag, Christian Mortensen |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Liver Cirrhosis
Adult Male medicine.medical_specialty Cirrhosis Adolescent Nutritional Supplementation Gastroenterology Young Adult 03 medical and health sciences 0302 clinical medicine Liver Cirrhosis/complications Internal medicine Ascites Paracentesis medicine Humans In patient Resting energy expenditure 030212 general & internal medicine Aged Retrospective Studies medicine.diagnostic_test business.industry Advanced cirrhosis Malnutrition Calorimetry Indirect Malnutrition/etiology Middle Aged medicine.disease Ascites/complications Surgery Female 030211 gastroenterology & hepatology medicine.symptom Energy Metabolism business Metabolic activity Follow-Up Studies |
| Zdroj: | Knudsen, A W, Krag, A, Nordgaard-Lassen, I, Frandsen, E, Tofteng, F, Mortensen, C & Becker, U 2016, ' Effect of paracentesis on metabolic activity in patients with advanced cirrhosis and ascites ', Scandinavian Journal of Gastroenterology, vol. 51, no. 5, pp. 601-609 . https://doi.org/10.3109/00365521.2015.1124282 |
| ISSN: | 1502-7708 0036-5521 |
| DOI: | 10.3109/00365521.2015.1124282 |
| Popis: | Objective Patients with decompensated cirrhosis often suffer from malnutrition. To enable appropriate nutritional supplementation a correct estimation of resting energy expenditure (REE) is needed. It is, however, unclear whether the volume of ascites should be included or not in the calculations of the REE. Material and methods In 19 patients with cirrhosis and ascites, measurements of REE by indirect calorimetry were performed before paracentesis, after paracentesis, and four weeks after paracentesis. Moreover, handgrip strength (HGS), dual X-ray absorptiometry (DXA), and biochemistry were assessed. Results Calculated and measured REE differed more than 10% in 63% of the patients at baseline. By including the weight of ascites in the calculation of REE, the REE was overestimated by 283 (-602-1381) kJ/day (p = 0.69). By subtracting the weight of ascites in the calculation of REE, it was underestimated by -379 (-1915 - 219) kJ/day, (p = 0.06). Patients in whom measured REE decreased after paracentesis had higher middle arterial pressure (MAP) (p = 0.02) and p-sodium (p = 0.02) at baseline. Low HGS (M |
| Databáze: | OpenAIRE |
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