Numerical study and theoretical performance limit of interconnected multi-capillary gas chromatography columns with perfectly ordered pillar patterns
| Autor: | Sander Jespers, Frederic Lynen, Gert Desmet |
|---|---|
| Přispěvatelé: | Faculty of Engineering, Faculty of Sciences and Bioengineering Sciences, Chemical Engineering and Industrial Chemistry, Industrial Microbiology, Centre for Molecular Separation Science & Technology, Department of Bio-engineering Sciences, Chemical Engineering and Separation Science |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Van Deemter equation
Fabrication Chromatography Gas Multi-capillary column 02 engineering and technology Computational fluid dynamics Kinetic energy 01 natural sciences Biochemistry Column (database) Analytical Chemistry Performance limit Pressure Computer Simulation Dispersion (water waves) Chromatography business.industry Chemistry 010401 analytical chemistry Organic Chemistry General Medicine Function (mathematics) 021001 nanoscience & nanotechnology 0104 chemical sciences Kinetics Bundle Radially-elongated pillars Microtechnology Microfabrication 0210 nano-technology business |
| Popis: | We present the results of a theoretical and numerical study of the chromatographic performance of a novel type of microfabricated GC column. The column consists of an array of rectangular flow diverters (pillars), creating a network of perfectly ordered, interconnected and tortuous flow-through paths. Using van Deemter and kinetic plots of simulated band broadening data, we could demonstrate that the proposed column structure performs as a bundle of parallel open-tubular capillaries with rectangular cross-section, connected by a regular pattern of channel-intermixing points that allow compensating for inevitable channel-to-channel differences in migration velocity without adding any significant dispersion themselves. The established kinetic plots also allowed to propose design rules for the optimal distance between the pillars as a function of the desired separation efficiency and the available column pressure. The simulations also allowed establishing an expression for the plate height as a function of the velocity of the carrier gas. Results are also compared to the results of a recent experimental study. (C) 2017 Elsevier B.V. All rights reserved. |
| Databáze: | OpenAIRE |
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