Correlation between left atrial expansion index and stroke subtype: A 10-Year Follow-Up Study
| Autor: | Shih-Hung Hsiao, Chao-Sheng Hsiao, Ying-Hao Ho |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Index (economics) 030204 cardiovascular system & hematology Correlation 03 medical and health sciences 0302 clinical medicine Left atrial Risk Factors Internal medicine Atrial Fibrillation medicine Humans Radiology Nuclear Medicine and imaging Sinus rhythm Atrial Appendage Heart Atria Prospective Studies Stroke business.industry Atrial fibrillation medicine.disease Quartile Intracranial Embolism Heart failure Cardiology Cardiology and Cardiovascular Medicine business 030217 neurology & neurosurgery Follow-Up Studies |
| Zdroj: | Echocardiography (Mount Kisco, N.Y.)REFERENCES. 38(6) |
| ISSN: | 1540-8175 |
| Popis: | PURPOSE Although left atrial (LA) expansion index predicts cardiovascular events, its efficacy for predicting cerebral events is unknown. METHODS This study enrolled 2205 patients who had sinus rhythm after echocardiography in their first visit. LA expansion index was calculated as (Volmax -Volmin ) x100%/Volmin , where Volmax was defined as maximal LA volume and Volmin as minimal LA volume. The study endpoint was ischemic stroke. Stroke subtype was classified as cardioembolic stroke (CE), noncardioembolic stroke with determined mechanism (NCE), or embolic stroke of undetermined source (ESUS). RESULTS Over a 10-year (mean 9.7 years) follow-up period, 128 (5.8%) participants reached endpoint, including 46 with CE, 33 with NCE, and 49 with ESUS. Regardless of stroke subtype, LA expansion index was lower in the event groups compared to the nonevent group. The lowest quartile of LA expansion index was associated with high CHA2 DS2 -VASc score at enrollment and more events, including CE, ESUS, atrial fibrillation (AF), heart failure, and all-cause mortality, relative to other quartiles. The LA expansion index was an independent predictor of CE (HR 0.82; 95% CI 0.723-0.912, per 10% increase in LA expansion index; P |
| Databáze: | OpenAIRE |
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