Corticosterone values and blood biochemistry in a model of streptozotocin-induced diabetes: the influence of dietary n6/n3 ratio
| Autor: | Tomislav Mašek, Kristina Starčević, Željko Pavičić, Gordana Gregurić Gračner, Slavko Žužul, Juraj Grizelj, Dora Ivšić Škoda, Alenka Dovč, Miroslav Benić |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
diabetes mellitus stress corticosterone n6/n3 ratio streptozotocin model General Veterinary Blood biochemistry business.industry medicine.disease Streptozotocin chemistry.chemical_compound Endocrinology chemistry Corticosterone Diabetes mellitus Internal medicine medicine business medicine.drug |
| Popis: | The study was carried out to investigate the influence of dietary n6/n3 ratio in streptozotocin (STZ) induced diabetes on serum biochemistry and corticosterone values in blood in 15 Wistar male rats assigned into three experimental groups, two diabetic and a control group (STZ-N3, STZ-N6, CON) fed with different diets (n6/n3 ratio: ≈ 1, n6/n3 ratio: ≈60, CON n6/n3 ratio: ≈7). Significantly higher values of alkaline phosphatase (AP) and beta-hydroxybutyrate (BHB) and lower levels for triglyceride and albumin were noticed in both STZ treated groups compared to the control. The values for blood urea nitrogen (BUN) were increased in only the STZ-N3 group compared to the control (P |
| Databáze: | OpenAIRE |
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