Brazilian Validation of the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Group (QLG) Computerised Adaptive Tests (CAT) Core
| Autor: | Gustavo Nader Marta, Ana Paula Alves Pereira, Tomás Yokoo Teodoro de Souza, Alice Roxo Nobre de Souza e Silva, David Rodrigues Ferreira Neto, Rafael Gadia, Samir Abdallah Hanna, Mauricio Silva, Everardo D. Saad, Fabiana Accioli Miranda Degrande, Rie Nadia Asso, Guilherme Nader-Marta, Bernhard Holzner, Morten Aagaard Petersen |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Validation study
Psychometrics Article Quality of life Neoplasms Surveys and Questionnaires otorhinolaryngologic diseases Medicine Humans RC254-282 patient-reported outcome measures Health related quality of life Core (anatomy) treatment business.industry Neoplasms. Tumors. Oncology. Including cancer and carcinogens social sciences humanities health-related quality of life Cross-Sectional Studies Health evaluation Cohort Quality of Life computerized adaptive test business Brazil Relative validity Demography |
| Zdroj: | Current Oncology Current Oncology, Vol 28, Iss 291, Pp 3373-3383 (2021) Volume 28 Issue 5 Pages 291-3383 |
| ISSN: | 1718-7729 1198-0052 |
| Popis: | Background: This study aimed to validate the Brazilian version of EORTC CAT Core and compare the Brazilian results with those from the original European EORTC CAT Core validation study. Methods: After validated translation, 168 cancer patients from Brazil receiving radiation therapy with or without chemotherapy was assessed. Translated EORTC CAT Core and all QLQ-C30 items were administered to patients using CHES (Computer-Based Health Evaluation System) before (T0) and after (T1) treatment initiation. The association between QLQ-C30 and CAT scores and ceiling/floor effects were estimated. Based on estimates of relative validity (cross-sectional, known-group differences and changes over time), relative sample-size requirements for CAT compared to QLQ-C30 were estimated. Results: Correlation coefficients between CAT and QLQ-C30 domains ranged from 0.63 to 0.93 except for dyspnoea, all coefficients were > 0.82 (corresponding figures were 0.81–0.93 in the European study). On average across domains, floor/ceiling was reduced by 10% using CAT (9% in the European study) corresponding to a relative reduction of 32% (37% in the European study). Analyses of known-group validity and responsiveness indicated that, on average across domains, the sample-size requirements may be reduced by 17% using CAT rather than QLQ-C30, without loss of power (28% in the European study). The Brazilian sample had less symptom/quality of life impairment than the European sample, which likely explains the lower sample-size reduction using CAT when comparing with the European sample. Conclusions: The results in the Brazilian cohort were generally similar to those from the European sample and confirm the validity and usefulness of the EORTC CAT Core. |
| Databáze: | OpenAIRE |
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