Frequency of chromosomal aberrations after exposure to γ-radiation of human chorionic villi
| Autor: | C. De Andreis, Giuseppe Simoni, M. Piantanida, F. Rossella, Roberta Salvi, S. Pariani, S. Orsini |
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| Rok vydání: | 1993 |
| Předmět: |
Chromosome Aberrations
Genetics Cytotrophoblast γ radiation Radiation dose In vitro exposure Dose-Response Relationship Radiation Biology Toxicology Molecular biology First trimester medicine.anatomical_structure Gamma Rays embryonic structures medicine Humans Chorionic villi Chorionic Villi Metaphase reproductive and urinary physiology Gamma irradiation |
| Zdroj: | Mutation Research/Environmental Mutagenesis and Related Subjects. 291:213-216 |
| ISSN: | 0165-1161 |
| DOI: | 10.1016/0165-1161(93)90161-r |
| Popis: | We investigated the chromosomal damage induced by in vitro exposure to γ-rays of uncultured first trimester chorionic villi. Frequency and types of chromosomal aberrations at increasing doses of radiation have been evaluated on cytotrophoblast spontaneous metaphases obtained after a short term incubation. Our results indicate a direct correlation between radiation dose and aberration frequency. |
| Databáze: | OpenAIRE |
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