THE EFFECTS OF TESTOSTERONE THERAPY COMBINED WITH SWIMMING EXERCISE ON ADIPOSE TISSUE AND BIOCHEMICAL PARAMETERS IN MALE OBESE WISTAR RATS

Autor: de Lima, D. G., da Silva, C. F., Freitas, A. G., da Silva, O. L.P., de Souza, F. M.A., Bortolini, M. J.S., Penha-Silva, N., Santos, F. G.A., de Carvalho, Y. K., Valenti, Vitor E. [UNESP], Silva, R. P.M.
Přispěvatelé: Univ Fed Acre, Coll Meta, Universidade Federal de Uberlândia (UFU), Universidade Estadual Paulista (UNESP), Federal University of Acre, College Meta
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Acta Endocrinol (Buchar)
Scopus
Popis: Made available in DSpace on 2022-04-28T17:21:35Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-07-01 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Company Finacier of Studies and Projects (FINEP) Context. Exercise and anabolic steroids are anticipated to promote fat mass reduction and so decrease the number of comorbidities related to excessive weight. Objective. The aim of this study was to verify the influence of aerobic exercise and the use of steroids on the accumulation of adipose tissue and on the biochemical limitations of Wistar rats nourished by a hypercaloric diet. Methods. Forty, young male Wistar rats were split into four groups: obese control (n=10), obese under treatment (n=10), obese under aerobic exercise (n=10) and obese under aerobic exercise and treatment (n=10). All animals were fed with a hypercaloric diet and animals under treatment received intramuscular testosterone. Body (weight and visceral fat) and blood (lipidogram, glucose, and liver enzymes) parameters were assessed. Results. The group treated with aerobic exercise and testosterone revealed a reduction in body weight and visceral, perirenal, retroperitoneal and epididymal fats, accompanied by the blood levels of glucose, lactate, LDLcholesterol, HDL-cholesterol, and lactate dehydrogenase; following high-intensity physical activity. Conclusion. The results support the theory that the combination of steroids and physical activity reduce side-effects of androgenic-anabolic hormones and convey benefits to some constraints. Univ Fed Acre, Postgrad Program Hlth Sci Western Amazon, Rio Branco, AC, Brazil Coll Meta, Rio Branco, Acre, Brazil Univ Fed Acre, Med Hlth & Sports Sci Ctr, Rio Branco, Brazil Univ Fed Uberlandia, Inst Biotechnol, Uberlandia, MG, Brazil Univ Fed Acre, Postgrad Program Sanit & Sustainable Anim Prod We, Rio Branco, AC, Brazil Sao Paulo State Univ, UNESP, Av Hygino Muzzi Filho 737, BR-17525900 Marilia, SP, Brazil Sao Paulo State Univ, UNESP, Av Hygino Muzzi Filho 737, BR-17525900 Marilia, SP, Brazil
Databáze: OpenAIRE
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