Polysomnographic characteristics of neuroleptic-induced akathisia
| Autor: | Scott E. Lukas, Paul E. Keck, Steven L. Cunningham, Rrobert B. Aranow, James I. Hudson, Joseph F. Lipinski, Gopinath Mallya, Harlyn G. Aizley |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Pharmacology
Adult Male Neuroleptic induced akathisia medicine.diagnostic_test business.industry Polysomnography Middle Aged Akathisia Sleep in non-human animals Pathophysiology Anesthesia Restless Legs Syndrome Medicine Humans Pharmacology (medical) In patient Female Neurology (clinical) Sleep onset medicine.symptom business Sleep Depression (differential diagnoses) Antipsychotic Agents |
| Zdroj: | Clinical neuropharmacology. 14(5) |
| ISSN: | 0362-5664 |
| Popis: | To investigate nocturnal leg movement activity and other polysomnographic features in patients with neuroleptic-induced akathisia (NIA), all-night polysomnography was performed in nine patients with NIA and compared with nine healthy individuals and eight unmedicated patients with depression. Patients with NIA displayed a pattern of leg movement activity during sleep similar to healthy individuals and depressed patients. In addition, eight of nine patients with NIA exhibited 10- to 40-second bursts of increased leg muscle tone before sleep onset. Although the significance of this finding is unclear, it is possible that it may be a pathophysiological correlate of NIA. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|