Outcomes and treatment of obstetrical antiphospholipid syndrome in women with low antiphospholipid antibody levels
| Autor: | Olivier Fain, Marie-Claire Boffa, Jérôme Stirnemann, Sylvie Chollet-Martin, Lionel Carbillon, Arsène Mekinian, Priscille Loire-Berson, E. Lachassinne, Pascale Nicaise-Roland |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Abortion Habitual Pediatrics medicine.medical_specialty Immunology Comorbidity Preeclampsia Young Adult Pre-Eclampsia Pregnancy Antiphospholipid syndrome Recurrent miscarriage medicine Humans Immunology and Allergy Adverse effect Fetal Death Retrospective Studies Aspirin Obstetrics business.industry Incidence Obstetrics and Gynecology Retrospective cohort study Heparin Low-Molecular-Weight Middle Aged Antiphospholipid Syndrome medicine.disease Treatment Outcome Reproductive Medicine Antibodies Antiphospholipid Gestation Female business |
| Zdroj: | Journal of Reproductive Immunology. 94:222-226 |
| ISSN: | 0165-0378 |
| DOI: | 10.1016/j.jri.2012.02.004 |
| Popis: | Our objective was to determine whether there is a relationship between low antiphospholipid (aPL) antibody levels and the obstetrical complications of antiphospholipid syndrome (APS) and to analyze the impact of conventional APS treatment in patients with low aPL levels. To this end, we retrospectively reviewed the files of all patients referred to our unit (2003-2010) for unexplained pregnancy morbidity, with an aPL test result. We compared patients with APS confirmed by Sapporo criteria (Group 1) with patients with APS-like obstetrical complications with an aPL titer below the intermediate titer (Group 2). Overall, 57 patients were included (25 in Group 1; 32 in Group 2). Obstetrical events were recurrent spontaneous abortion |
| Databáze: | OpenAIRE |
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