The Relationship of Fuhrman Nuclear Grade, Tumor Stage and Sarcomatoid Differentiation with Survival in Renal Cell Carcinomas

Autor: Mustafa Kaplan, A. Kemal Kutlu, Burcu Tokuç, Fulya Oz Puyan, Ebru Tastekin, Filiz Ozyilmaz, Vuslat Yurut Caloglu, Ufuk Usta
Rok vydání: 2012
Předmět:
Zdroj: Balkan Medical Journal, Vol 29, Iss 1, Pp 14-20 (2012)
Volume: 2012, Issue: 1 14-20
Balkan Medical Journal
ISSN: 2146-3131
2146-3123
DOI: 10.5152/balkanmedj.2011.009
Popis: Objective: Renal cell carcinoma derived from tubular epithelium is one of the malignant tumors of the kidney. We have investigated the histological features, pathological stage, nuclear grade and sarcomatoid differentiation of these tumors. Material and Methods: Histological slides from seventy-eight nephrectomy specimens diagnosed as renal cell carcinoma between 2000 and 2008 were reevaluated according to the 2004 World Health Organization classification system of kidney tumors. Reclassified cases were collected in five groups and were scored for Fuhrman nuclear grading, stage, sarcomatoid differentiation and survival rate. Results: In our study, cases with high nuclear grade, advanced stage and sarcomatoid differentiation revealed poor survival rates (p
Databáze: OpenAIRE