| Autor: |
Thomas G. Schulze, Georg Auburger, Sven Cichon, Fermin Perez Perez, Markus M. Nöthen, Robert Fuerst, Ivo Kremensky, Vesselin M. Chorbov, Thomas F. Wienker, Rami Abou Jamra, Francisco del Rio, Fermín Mayoral, Radka Kaneva, Marcella Rietschel, George Onchev, María J. González, Fabio Rivas, Christian Kostov, Jesus Haro, Vihra Milanova, Susana Gil, Sebastian Sans, Vessela Stoyanova, Amelia Nikolova-Hill, Guillermo Orozco Diaz, Peter Propping, Assen Jablensky, Johannes Schumacher, Francisco Cabaleiro |
| Rok vydání: |
2007 |
| Předmět: |
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| Zdroj: |
American journal of human genetics. 81(5) |
| ISSN: |
0002-9297 |
| Popis: |
We present the first genomewide interaction and locus-heterogeneity linkage scan in bipolar affective disorder (BPAD), using a large linkage data set (52 families of European descent; 448 participants and 259 affected individuals). Our results provide the strongest interaction evidence between BPAD genes on chromosomes 2q22-q24 and 6q23-q24, which was observed symmetrically in both directions (nonparametric LOD [NPL] scores of 7.55 on 2q and 7.63 on 6q; P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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