Isolation and structure of cyclosenegalins A and B, novel cyclopeptides from the seeds of Annona senegalensis
| Autor: | Mamadou Badiane, Bernard Bodo, Lionel Dubost, Alassane Wélé, Jean-Louis Pousset, Catherine Guette, Yanjun Zhang, Christelle Caux, Jean-Paul Brouard |
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| Přispěvatelé: | Laboratoire de chimie et biochimie des substances naturelles, Muséum national d'Histoire naturelle (MNHN)-Centre National de la Recherche Scientifique (CNRS) |
| Rok vydání: | 2002 |
| Předmět: |
chemistry.chemical_classification
chemistry.chemical_compound biology Chemistry Stereochemistry General Medicine Methanol Annona senegalensis biology.organism_classification Mass spectrometry Chemical decomposition Cyclic peptide [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry Molecular Biology/Biomolecules [q-bio.BM] |
| Zdroj: | Journal of the Chemical Society. Perkin transactions 1. Journal of the Chemical Society. Perkin transactions 1., 2002, 2002, pp.2712-2718 |
| ISSN: | 1364-5463 1472-7781 |
| DOI: | 10.1039/b205035h |
| Popis: | Two new cyclopeptides, cyclosenegalin A, cyclo(Pro1-Gly2-Leu3-Ser4-Ala5-Val6-Thr7-) (1) and cyclosenegalin B, cyclo(Pro1-Gly2-Tyr3-Val4-Tyr5-Pro6-Pro7-Val8-) (2), have been isolated from the methanol extract of the seeds of Annona senegalensis Pers., along with the known cyclic peptide, glabrin A. The structures were elucidated on the basis of the MS/MS fragmentation, using a Q-TOF mass spectrometer equipped with an ESI source, chemical degradation and extensive 2D-NMR. |
| Databáze: | OpenAIRE |
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