Evaluating selective laser trabeculoplasty versus argon laser trabeculoplasty in pseudoexfoliation glaucoma patients
| Autor: | Jin Soo A. Song, Marcelo T. Nicolela, Paul E Rafuse, Jayme R Vianna, Lesya M. Shuba |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Intraocular pressure medicine.medical_specialty Trabeculoplasty genetic structures Open angle glaucoma medicine.medical_treatment Gonioscopy Glaucoma Trabeculectomy Exfoliation Syndrome 03 medical and health sciences 0302 clinical medicine Ophthalmology Glaucoma surgery medicine Humans Intraocular Pressure Aged Retrospective Studies Aged 80 and over Glaucoma medication medicine.diagnostic_test business.industry Retrospective cohort study General Medicine Middle Aged Plastic Surgery Procedures medicine.disease eye diseases 030221 ophthalmology & optometry Female Laser Therapy sense organs business 030217 neurology & neurosurgery Follow-Up Studies |
| Zdroj: | Canadian Journal of Ophthalmology. 53:70-75 |
| ISSN: | 0008-4182 |
| DOI: | 10.1016/j.jcjo.2017.07.004 |
| Popis: | Objective Laser trabeculoplasty effectively reduces intraocular pressure (IOP) in primary open angle glaucoma, with argon laser trabeculoplasty (ALT) and selective laser trabeculoplasty (SLT) showing equivalent outcomes. However, it is unclear which laser modality is more effective in pseudoexfoliation (PXE) glaucoma. This study aims to compare the effectiveness of ALT and SLT in PXE glaucoma. Design Retrospective cohort study. Methods A chart review evaluating patients diagnosed with PXE glaucoma and treated with laser trabeculoplasty from 2005-2015. Patients with previous glaucoma surgery, other forms of secondary glaucoma, ocular surgery within six months of initial trabeculoplasty or lacking preoperative IOP measurements were excluded. Post-laser measurements were recorded until 24 months after initial intervention. Follow-up data was censored if the patient underwent a subsequent trabeculoplasty different from initial laser treatment. Results We included 84 patients in the ALT group and 123 in the SLT group. The mean (SD) baseline IOP values were 22.7 (±5.6) and 21.6 (±4.8) respectively (p = 0.11), while number of medications were 2.0 (±1.0) and 1.8 (±1.3) for ALT and SLT groups respectively (p = 0.36). The mean IOP reduction for the ALT group at 6, 12 and 24 months were 5.2 (±6.1), 5.4 (±6.9), and 4.9(±7.7) respectively. The corresponding values for the SLT group were 3.4 (±5.2), 3.8 (±4.6), and 4.6 (±6.5). Comparison of both lasers at each time point revealed no significant differences (p > 0.05) in IOP reduction or reduction of glaucoma medication. Conclusions Our study showed equivalent efficacy between ALT and SLT in patients with PXE glaucoma. |
| Databáze: | OpenAIRE |
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