Nontumorous decrease in Tc-99m GSA accumulation
| Autor: | Susumu Kanazawa, Shiro Akaki, Masatoshi Tsunoda, Masahiro Kuroda, Yoshio Hiraki, Izumi Togami, Yoshihiro Okumura, Yoshihiro Takeda |
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| Rok vydání: | 2000 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Carcinoma Hepatocellular Cholangiocarcinoma Liver Function Tests Fibrosis Massive Hepatic Necrosis Occlusion medicine Humans Tissue Distribution Radiology Nuclear Medicine and imaging Thrombus Fulminant hepatitis Technetium Tc 99m Aggregated Albumin neoplasms Aged Aged 80 and over Tomography Emission-Computed Single-Photon Hepatitis business.industry Liver Diseases Liver Neoplasms General Medicine Middle Aged medicine.disease Bile Ducts Intrahepatic Bile Duct Neoplasms Liver Biliary Stasis Technetium Tc 99m Pentetate Female Tc-99m-GSA Radiopharmaceuticals business |
| Zdroj: | Annals of Nuclear Medicine. 14:477-483 |
| ISSN: | 1864-6433 0914-7187 |
| DOI: | 10.1007/bf02988294 |
| Popis: | Nontumorous decrease in99mTc-GSA accumulation has not been well covered in the literature. Understanding of this phenomenon is, however, essential for accurate evaluation of regional hepatic function. Scintigrams (transaxial SPECT) of 269 patients who underwent99mTc-GSA liver scintigraphy were reviewed for the presence of nontumorous decreases in99mTc-GSA accumulation. Nontumorous decreases in99mTc-GSA accumulation were seen in 32 of 269 patients (12%). In 16 of the 32 patients (6%), nontumorous decreases in99mTc-GSA accumulation corresponded to regional decrease in portal venous flow. The causes of such decrease in portal venous flow were portal thrombus of hepatocellular carcinomas in eight patients, portal venous stenosis or occlusion by hilar cholangiocarcinomas in five patients, inter alia. In eight patients (3%), the regions with decreased99mTc-GSA accumulation correlated with massive hepatic necrosis in fulminant hepatitis, scar in hepatitis, or confluent fibrosis in cirrhotic liver. In two patients (0.7%) with hilar cholangiocarcinomas, the possible causes of lobar decrease in99mTc-GSA accumulation were thought to be lobar decrease in portal venous flow, lobar biliary stasis, or both. In four patients (1.5%), the exact causes of nontumorous decrease in99mTc-GSA accumulation could not be determined. |
| Databáze: | OpenAIRE |
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