Quantitative performance of forward fill/flush differential flow modulation for comprehensive two-dimensional gas chromatography
| Autor: | Chantal Lorentz, Vincent Souchon, Maxime Moreaud, Christophe Geantet, Aleksandra Lelevic |
|---|---|
| Přispěvatelé: | IFP Energies nouvelles (IFPEN), Institut de recherches sur la catalyse et l'environnement de Lyon (IRCELYON), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Work (thermodynamics)
Chromatography Gas Chromatography Chemistry 010401 analytical chemistry Organic Chemistry Flow (psychology) Temperature Process (computing) General Medicine Models Theoretical 010402 general chemistry 01 natural sciences Biochemistry Column (database) 0104 chemical sciences Analytical Chemistry Paraffin Modulation [SDE]Environmental Sciences Range (statistics) Two-dimensional gas [CHIM]Chemical Sciences Differential (infinitesimal) |
| Zdroj: | Journal of Chromatography A Journal of Chromatography A, Elsevier, 2020, 1626, pp.461342. ⟨10.1016/j.chroma.2020.461342⟩ |
| ISSN: | 0021-9673 1873-3778 |
| DOI: | 10.1016/j.chroma.2020.461342⟩ |
| Popis: | International audience; GC × GC is an advanced separation technique allowing to achieve quantitative and qualitative characterization of complex samples. In order to perform two-dimensional separation, the system must provide suitable peak modulation which will direct short impulses of first column flow towards the second column. Forward fill/ flush differential flow modulation is a cost effective and no cryogen requiring approach which allows modulation over a wide range of analytes with very different boiling points. However, optimization of the flow modulation process can be difficult to understand and quantification performance might be compromised if the parameters of the modulation process are not properly set. Modulated peak shape can be a good indication of the efficiency of the modulation process, however it is not sufficient to guarantee good quantification. Different average velocities in the beginning and the end of the thermally programmed GC run may cause different efficiency of the modulation process in various parts of the chromatogram. The purpose of this work is to investigate quantitative performance of the forward/fill flush modulation and delineate parameters that determine the effectiveness of the modulation process and its ability to properly reflect the quantitative composition of the investigated sample. |
| Databáze: | OpenAIRE |
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